The European Agency for the Evaluation of Medicinal Products Veterinary Medicines and Information Technology Unit

1. Prednisolone is a synthetic glucocorticosteroid. In veterinary medicine, prednisolone (as the free alcohol) is included as an ingredient in a number of antibiotic preparations, which are indicated for intramammary administration for the treatment of bovine mastitis. The usual dose corresponds to 10 mg prednisolone per infected quarter. Treatment may be repeated at 12-hour intervals for a maximum of 3 treatments.